Peripermeabilizationcontexts

Peripermeability is a term occasionally used to describe the permeability of a boundary or periphery of a system to the passage of substances. It is not a standard designation in most scientific literatures; more common terms include permeability, membrane permeability, or surface transport, which describe transport across well-defined boundaries rather than the outer region itself.

In biology, permeability typically refers to movement across membranes. When writers use "peripermeability," they may be emphasizing transport in the boundary layer or near the external surface, though most discussions address the overall membrane permeability or surface exchange separately.

In materials science and engineering, the concept can relate to transport through the near-surface region of a solid, such as diffusion into a porous coating or along a boundary layer. Measurements often involve a permeability coefficient and analysis via Fick's laws or related transport models.

Factors influencing peripermeability include pore size and distribution, molecular size and shape, polarity and charge, temperature, and boundary-material interactions. In biological contexts, lipid composition and membrane proteins govern effective permeability; in solids, porosity, tortuosity, and surface chemistry are key.

Applications span drug delivery near tissue surfaces, filtration and separation processes, corrosion science, and the design of coatings with controlled boundary transport. The term remains uncommon, and users typically specify the boundary, surface, or membrane permeability to avoid ambiguity.