Peptidanalogues
Peptidanalogues are synthetic or naturally occurring compounds that are structurally similar to peptides but possess modifications designed to enhance stability, bioavailability, or specificity. These analogues are often developed to mimic the biological activity of endogenous peptides, such as hormones, neurotransmitters, or signaling molecules, while overcoming limitations associated with natural peptides, including rapid degradation and poor pharmacokinetics.
Peptidanalogues are used extensively in pharmaceutical research and drug development. They can exhibit improved resistance to
Examples of peptidanalogues include analogs of insulin used in diabetes management, such as insulin lispro, and
The design of peptidanalogues involves techniques such as structure-activity relationship (SAR) studies, molecular modeling, and chemical
Overall, peptidanalogues are a vital class of compounds that extend the utility of peptides in medical and