Palladium0PalladiumIIZyklus
The Palladium0PalladiumIIZyklus, often referred to as the palladium(0)-palladium(II) catalytic cycle, is a fundamental mechanistic pathway in organometallic chemistry. It describes the series of reactions involving a palladium catalyst in two different oxidation states, zero and plus two. This cycle is crucial for many palladium-catalyzed cross-coupling reactions, such as the Suzuki, Heck, and Sonogashira couplings, which are widely used in the synthesis of complex organic molecules.
The cycle typically begins with an oxidative addition step, where a palladium(0) species reacts with an organic