PLLsynteesiä

PLLsynteesiä refers to the synthesis of polylysine. Polylysine is a polymer made up of lysine amino acid residues. It can be synthesized biologically through fermentation by certain microorganisms, such as Streptomyces albulus, or chemically. Chemical synthesis typically involves activating the carboxyl group of lysine or its derivatives, followed by polymerization. The resulting polylysine can exist in different forms depending on the stereochemistry of the lysine units, such as poly(L-lysine) and poly(D-lysine). These polymers have a positively charged side chain due to the amine group of lysine, which contributes to their unique properties and diverse applications. Polylysine is known for its antimicrobial activity and is used as a food preservative. It also finds applications in drug delivery systems, tissue engineering, and as a gene delivery vector due to its ability to bind to nucleic acids. The specific properties and uses of polylysine are often dependent on its molecular weight and the ratio of L- to D-lysine units. Research continues to explore new methods for synthesizing polylysine with controlled structures and enhanced functionalities for various biomedical and industrial purposes.