PDZcontaining
PDZ-containing proteins are a class of proteins that contain a PDZ (PSD-95/Dlg/ZO-1) domain. The PDZ domain is a small, structurally conserved motif that is found in a wide variety of proteins, particularly those involved in cell signaling and synaptic transmission. The PDZ domain typically consists of about 80-100 amino acids and is characterized by a beta-sheet structure with a hydrophobic core.
PDZ domains are known for their ability to bind to specific motifs in target proteins, often involving
PDZ-containing proteins are involved in numerous biological functions. For example, in the nervous system, PDZ domains
The study of PDZ-containing proteins has provided valuable insights into the molecular mechanisms underlying various physiological