PSD95DlgZO1
PSD95DlgZO1 refers to a protein complex formed by the interaction of PSD95 (Postsynaptic density protein 95) andDlg (Discs large) family proteins, including ZO1 (Zonula occludens 1). PSD95 is a crucial scaffolding protein found in the postsynaptic density of excitatory synapses in the central nervous system. It plays a vital role in organizing neurotransmitter receptors, ion channels, and signaling molecules at the synapse. Dlg proteins, such as ZO1, are also known as MAGUKs (Membrane-associated guanylate kinase) and are involved in cell adhesion and signaling.
The interaction between PSD95 and Dlg proteins, particularly ZO1, is significant in assembling and stabilizing multiprotein