OGlcNActransferaasi
OGlcNActransferaasi is an enzyme that plays a crucial role in the O-GlcNAcylation of proteins. O-GlcNAcylation is a dynamic post-translational modification where a single N-acetylglucosamine sugar molecule is attached to serine or threonine residues of proteins. This process is analogous to phosphorylation and is known to influence a wide range of cellular functions, including gene transcription, signal transduction, and protein degradation.
The enzyme OGlcNACT, also known as O-GlcNAc Transferase (OGT), catalyzes the transfer of UDP-N-acetylglucosamine to the
OGlcNACT is a large and complex enzyme with multiple domains that contribute to its substrate specificity