NoyesWhitneytörvény
The Noyes Whitney law, also known as the Noyes Whitney equation, is an empirical relationship used in pharmaceutical science to describe the dissolution rate of a solid drug in a liquid medium. Developed by William Noyes and William Whitney in 1903, the equation models how quickly a drug dissolves, which is a critical factor in its bioavailability and therapeutic effectiveness.
The Noyes Whitney equation states that the rate of dissolution is directly proportional to the surface area
This equation highlights several key factors influencing dissolution. A larger surface area, achieved through smaller particle
The Noyes Whitney equation is fundamental in understanding and predicting drug dissolution. It is widely applied