Nitroxylcontaining

Nitroxylcontaining refers to chemical compounds that contain the nitroxyl functional group. The nitroxyl group has the chemical formula NO-. This group is an anion, meaning it carries a negative charge. It is an isoelectronic species with the nitrosonium cation (NO+) and molecular nitrogen (N2). In organic chemistry, nitroxyl can be considered as a derivative of hydroxylamine (NH2OH) where one hydrogen atom is replaced by an oxygen atom, or as a deprotonated form of nitroxyl radical (HNO).

The nitroxyl group is a relatively reactive species and plays a role in various chemical and biochemical processes. It is an important intermediate in the metabolism of nitric oxide (NO) in biological systems. In biological contexts, nitroxyl can be generated from nitric oxide under reducing conditions or through enzymatic pathways. It has been studied for its potential physiological effects, which can differ from those of nitric oxide. For example, nitroxyl can influence cardiac contractility and vascular tone.

In synthetic chemistry, nitroxylcontaining compounds can be synthesized through various methods, often involving oxidation or reduction reactions of nitrogen-containing precursors. These compounds can be used as intermediates in the synthesis of more complex molecules or studied for their unique chemical properties. The stability and reactivity of nitroxylcontaining species are highly dependent on their molecular environment.