Nierglomerulusfiltratie

Nierglomerulusfiltratie, often abbreviated as GFR, refers to the rate at which blood is filtered by the glomeruli in the kidneys. The glomerulus is a tiny network of capillaries located within Bowman's capsule, which together form a nephron, the functional unit of the kidney. This filtration process is the first step in urine production. As blood flows through the glomerulus, water, salts, glucose, urea, and other small molecules are forced from the blood into Bowman's capsule, forming the glomerular filtrate. Larger molecules, such as proteins and blood cells, are too large to pass through the filtration barrier and remain in the blood. GFR is a crucial indicator of kidney function. A healthy GFR signifies that the kidneys are effectively filtering waste products and excess fluid from the blood. Conversely, a decreased GFR can indicate kidney damage or disease. Several factors can influence GFR, including blood pressure, kidney blood flow, and the permeability of the glomerular filtration membrane. Measurement of GFR is typically achieved through blood tests that assess the level of creatinine, a waste product produced by muscle metabolism, and then using a formula to estimate the filtration rate. Doctors use GFR values to diagnose and monitor kidney conditions, as well as to guide treatment decisions.