Neuroinflammatoriset

Neuroinflammatoriset refers to the inflammatory processes occurring within the nervous system. This phenomenon involves the activation of immune cells in the brain and spinal cord, primarily microglia and astrocytes. While inflammation is a crucial protective response to injury or infection, chronic or dysregulated neuroinflammation can be detrimental.

The activation of neuroinflammatory pathways can be triggered by various factors, including neurodegenerative diseases like Alzheimer's and Parkinson's, traumatic brain injury, stroke, and infections affecting the central nervous system. These activated immune cells release a cascade of signaling molecules, including cytokines and chemokines, which can have both beneficial and harmful effects. Initially, these molecules aim to clear debris, repair damage, and fight off pathogens. However, persistent release can lead to neuronal damage, synaptic dysfunction, and the exacerbation of disease pathology.

Research into neuroinflammation is a rapidly evolving field. Understanding the complex interplay between immune cells and neural tissue is crucial for developing therapeutic strategies for a range of neurological disorders. Modulating neuroinflammatory responses, either by suppressing excessive inflammation or enhancing beneficial aspects, is a key focus in current neuroscience research. The identification of specific inflammatory markers and pathways offers potential targets for diagnostic tools and novel treatments.