NNdimethylaminoethanol

N,N-Dimethylaminoethanol, also known as DMAE or dimethylaminoethanol, is an organic compound with the formula C4H11NO. It consists of a dimethylamino group attached to a two-carbon hydroxy chain, making it a tertiary amine bearing a hydroxyl group. This structure gives it both basic and alcohol functional properties.

DMAE is commonly prepared by the alkylation of dimethylamine with ethylene oxide, a route that yields N,N-dimethylaminoethanol after workup. Alternative methods include methylation of ethanolamine or related amine alkylation processes. The compound is typically used as a reactive intermediate in organic synthesis.

Physically, N,N-dimethylaminoethanol is a colorless liquid that is miscible with water and many organic solvents. It behaves as a weak base and can form salts with acids. As with many amines, it can be corrosive to metals and may irritate skin, eyes, and the respiratory tract if proper precautions are not taken.

In industrial applications, DMAE serves as a chemical intermediate for the production of surfactants, quaternary ammonium salts, and various pharmaceutical or polymeric intermediates. It is also used as a building block in the synthesis of other amines and related compounds, and can be employed in formulations as a reactive amine component.

Safety and handling guidelines emphasize use in well-ventilated areas, with appropriate personal protective equipment (gloves, goggles). It should be kept away from incompatible materials, particularly oxidizers, and stored in suitable containers. Regulatory status varies by jurisdiction, reflecting its characterization as a hazardous chemical and its role as an industrial intermediate.