NETtransporterin
NETtransporterin is a family of integral membrane proteins responsible for the reuptake of neurotransmitters from the synaptic cleft back into the presynaptic neuron. These proteins play a crucial role in regulating neurotransmission by terminating the signal and allowing for the recycling of neurotransmitters. There are several subtypes of NETtransporterin, each with specific affinities for different neurotransmitters. For example, DAT (Dopamine Transporter) specifically transports dopamine, while SERT (Serotonin Transporter) transports serotonin. NET (Norepinephrine Transporter) transports norepinephrine. These transporters are typically found embedded in the plasma membrane of neurons and glial cells.
The mechanism of action for NETtransporterin involves a process known as secondary active transport. They utilize