NEJM

The New England Journal of Medicine (NEJM) is an American peer‑reviewed medical journal published by the Massachusetts Medical Society. Based in Boston, it is one of the oldest and most widely read medical journals in the world. NEJM publishes original research, review articles, editorials, and other material intended to inform clinical practice and health policy.

NEJM was established in the early 19th century by the Massachusetts Medical Society. Over more than two centuries it has played a central role in reporting clinical trials and medical advances that have shaped modern medicine. The journal is known for its rigorous editorial standards and selective publication process.

The scope of NEJM covers a broad range of clinical medicine with a focus on studies that inform patient care and therapeutic decision‑making. Content includes original research articles—often including randomized controlled trials and observational studies—review articles, brief reports, editorials, and correspondences. Topics span cardiology, infectious disease, oncology, general medicine, pediatrics, public health, and beyond.

Articles undergo a formal peer‑review process and editorial evaluation. Accepted papers are published online and in weekly print issues, with rapid online publication available for timely findings. NEJM generally operates on a subscription model, with some content subject to open access options and broader online availability through its platform NEJM.org.

NEJM is widely regarded as a premier source of clinical evidence and medical knowledge. Its high citation rates and influence on clinical guidelines contribute to its prominent status in medicine, affecting practitioners, researchers, and health systems worldwide.