NAT2geeneissä
NAT2geeneissä refers to genetic variations within the NAT2 gene. The NAT2 gene provides instructions for making an enzyme called N-acetyltransferase 2, which plays a crucial role in the metabolism of many drugs and environmental chemicals. This enzyme is involved in the acetylation process, which can either inactivate or activate certain substances.
Variations in the NAT2 gene can lead to differences in how effectively individuals metabolize these substances.
These differences in metabolic rates can have significant implications for drug efficacy and toxicity. For example,