NADPlle
NADPH (nicotinamide adenine dinucleotide phosphate) is a crucial coenzyme found in all living cells, playing a central role in anabolic reactions, biosynthetic processes, and cellular defense mechanisms. It is a reduced form of NADP+ (nicotinamide adenine dinucleotide phosphate) and functions as a hydride ion carrier in redox reactions, transferring electrons during metabolic pathways.
NADPH is generated primarily through the pentose phosphate pathway (PPP), which occurs in the cytoplasm of cells.
In addition to its role in biosynthesis, NADPH is vital for maintaining the reduced state of glutathione,
NADPH also contributes to fatty acid and cholesterol synthesis, as it provides reducing power for enzymes like
Deficiencies in NADPH production or function can impair cellular metabolism, leading to oxidative stress, impaired biosynthesis,