NADPHabhängige
NADPHabhängige refers to a group of enzymes that utilize nicotinamide adenine dinucleotide phosphate (NADPH) as a cofactor for their catalytic activity. NADPH is a crucial reducing agent in cells, playing a vital role in various metabolic pathways, including biosynthesis, detoxification, and the maintenance of redox homeostasis. These enzymes are essential for a wide range of biological processes.
One of the primary functions of NADPH-dependent enzymes is in anabolic pathways, such as the synthesis of
Another significant role is in detoxification. Enzymes like cytochrome P450 reductases, which are NADPH-dependent, are involved
Furthermore, NADPH-dependent enzymes are critical for cellular defense against oxidative stress. Glutathione reductase, which uses NADPH,