Monogramin

Monogramin is a naturally occurring alkaloid found in the leaves of the plant species *Mitragyna speciosa*, commonly known as kratom. It is one of many indole alkaloids present in kratom, and while it has been studied, its pharmacological properties and effects are not as well-understood as those of more prominent kratom alkaloids like mitragynine and 7-hydroxymitragynine.

Research into monogramin is limited, and its contribution to the overall effects attributed to kratom is not clearly defined. Like other alkaloids in kratom, monogramin may interact with opioid receptors in the brain, though the specific binding affinity and efficacy of monogramin are not extensively documented in scientific literature. Its presence in kratom extract varies, and the concentration can be influenced by factors such as plant genetics, growing conditions, and harvesting methods.

Further scientific investigation is required to fully elucidate the chemical structure, biosynthesis, and physiological effects of monogramin. Understanding the roles of all kratom alkaloids, including lesser-known ones like monogramin, is crucial for a comprehensive scientific understanding of the plant and its constituents.