Mikrotubulusnucleációs
Mikrotubulusnucleációs refers to the process by which microtubules are initiated and assembled. Microtubules are essential components of the cytoskeleton, playing roles in cell shape, intracellular transport, and cell division. Their formation is a highly regulated process, and it begins with the formation of a small, stable seed structure. This seed is typically composed of gamma-tubulin, which is found in a ring complex. These gamma-tubulin ring complexes act as nucleation sites, recruiting alpha- and beta-tubulin heterodimers. These heterodimers then assemble onto the growing end of the microtubule, a process known as polymerization.
The primary site of microtubule nucleation in eukaryotic cells is the centrosome. The centrosome contains two