Mastsoluja

Mastsoluja is a term that refers to mast cells, which are a type of white blood cell found in connective tissues throughout the body. These cells play a crucial role in the immune system, particularly in allergic reactions and defense against pathogens. Mast cells contain granules filled with various bioactive substances, including histamine, heparin, and proteases.

When the body encounters an allergen or a pathogen, mast cells can be activated. This activation leads to the release of their stored granules, a process known as degranulation. The released substances then trigger a cascade of inflammatory responses. Histamine, for instance, causes vasodilation and increased vascular permeability, leading to symptoms like redness, swelling, and itching. Heparin acts as an anticoagulant, and proteases can break down tissues.

Mast cells are found in high concentrations in tissues that are close to the external environment, such as the skin, lungs, and gastrointestinal tract. This strategic location allows them to act as sentinels, quickly responding to threats. Their involvement extends beyond allergies; they are also implicated in wound healing, angiogenesis, and the regulation of immune responses. Dysregulation of mast cell activity can contribute to various inflammatory and allergic diseases.