Massepektrometri

Massepektrometri is a branch of analytical chemistry that involves the separation, detection, and quantification of ions based on their mass-to-charge ratio. The name is derived from the Greek words "massa" meaning mass, and "pektros" meaning circulating current of electric charge. This technique is widely used in various fields such as pharmaceuticals, environmental science, and materials research.

Principle of Massepektrometri:

Massepektrometri is based on the principle that ions of different mass-to-charge ratios travel at different rates when accelerated by an electric field in a vacuum. By ionizing a sample and separating it based on its mass-to-charge ratio using a magnetic sector or quadrupole analyzer, massepektrometri can produce a detailed profile of the ions present in the sample.

Types of Massepektrometri:

There are two main types of massepektrometri: quadrupole and time-of-flight (TOF) massepektrometry. Quadrupole massepektrometry involves the use of a quadrupole lens to focus the ions based on their mass-to-charge ratio. TOF massepektrometry involves the measurement of the time it takes for ions to travel a certain distance, with lighter ions selecting faster.

Applications of Massepektrometri:

Massepektrometri is widely used in various applications, including pharmaceuticals, biomedical research, and environmental research. It is used in the detection and quantification of trace amounts of pollutants, metabolism, and pharmaceuticals in biological fluids. Additionally, it is used in food safety testing, monitoring of industrial pollutants, and detection of narcotics.

Advantages:

Massepektrometri has several advantages, including high sensitivity, specificity, and reproducibility. It can also be used in conjunction with other analytical techniques such as chromatography.