MDA9Syntenin

MDA9Syntenin, also known as syntenin or syndecan binding protein 1 (SDCBP1), is a protein encoded by the SDCBP gene. It is a ubiquitously expressed protein found in various tissues and cell types. MDA9Syntenin is a multi-domain protein that plays a significant role in cell adhesion, migration, and signal transduction.

The protein consists of several functional domains, including PDZ domains and a cysteine-rich domain. These domains enable MDA9Syntenin to interact with a variety of other proteins, forming molecular complexes that are crucial for cellular processes. It is known to bind to syndecans, a family of cell surface proteoglycans, and to other proteins involved in cytoskeletal organization and cell-cell junctions.

MDA9Syntenin has been implicated in a range of cellular functions. It contributes to the regulation of cell migration and invasion, making it relevant in developmental processes and disease states like cancer. It also participates in the trafficking of vesicles and the organization of the actin cytoskeleton. Furthermore, MDA9Syntenin has been linked to the regulation of gene expression and inflammatory responses. Its diverse interactions and roles highlight its importance as a versatile scaffolding protein within the cell.