MCPIP1
MCPIP1, also known as Monocyte chemotactic protein-induced protein 1, is a protein encoded by the MCPIP1 gene. It is a member of the zinc-finger protein family and plays a role in regulating cellular responses to stress and inflammation. MCPIP1 contains a UBL-like domain, a zinc-finger domain, and a RING-type zinc-finger motif, suggesting it has E3 ubiquitin ligase activity.
The expression of MCPIP1 is induced by inflammatory stimuli, such as tumor necrosis factor-alpha (TNF-α) and
Functional studies have indicated that MCPIP1 can act as a negative regulator of inflammatory signaling pathways,