MAP1C

MAP1C, also known as microtubule-associated protein 1C, is a protein encoded by the MAP1C gene. This gene is located on chromosome 15 in humans. MAP1C is a member of the microtubule-associated protein family, which plays a crucial role in regulating the assembly and dynamics of microtubules. Microtubules are essential components of the cytoskeleton, providing structural support to cells and participating in intracellular transport, cell division, and cell motility.

MAP1C is a large protein that can interact with microtubules, influencing their stability and organization. It is particularly abundant in neurons and plays a significant role in neuronal development and function. Studies suggest that MAP1C is involved in axon growth and guidance, as well as the formation and maintenance of dendritic spines. Its interaction with other cytoskeletal proteins and signaling molecules is thought to be important for these processes.

Mutations or alterations in MAP1C expression have been associated with certain neurological disorders, although the exact mechanisms are still under investigation. Research into MAP1C continues to explore its diverse functions within the cell and its potential implications in various biological processes and disease states. The protein's complex interactions and widespread presence in neuronal structures highlight its importance in the nervous system.