Keelesealases

Keelesealases are a hypothetical class of enzymes proposed in speculative biochemistry and science fiction contexts to catalyze sealing reactions at material interfaces. The term combines “keel,” a fictional element in some speculative frameworks, with the -ase suffix used for enzymes, and it has no formal standing in official enzyme nomenclature.

In proposed models, keelesealases would act as ligases or polymerases at interfaces between polymers or tissues, promoting covalent cross-links or rapid adhesion to form an impermeable seal. Mechanisms are entirely hypothetical, and suggested substrates and cofactors vary across speculative schemes. Potential applications discussed include self-healing materials, surgical adhesives, and restoration of damaged polymers or packaging, though there is no experimental evidence to support real-world existence. The concept remains mainly within thought experiments and fiction, and faces challenges such as biocompatibility and regulatory acceptance if ever pursued.

See also self-healing materials, biomimetic adhesives, and polymer chemistry.