KRT110

KRT110, also known as Keratin 110, is a protein encoded by the KRT110 gene in humans. It is a type II keratin, meaning it is a basic keratin that typically pairs with acidic type I keratins to form intermediate filaments. These filaments are essential structural components of epithelial cells, providing mechanical strength and maintaining cell integrity.

The KRT110 gene is part of a larger family of keratin genes located on chromosome 12. Keratins are a group of fibrous structural proteins that form the hard and soft tissues of the body, including hair, nails, and the outer layer of skin. The specific functions of KRT110 are still being investigated, but it is believed to play a role in the development and maintenance of certain epithelial tissues.

Mutations in keratin genes, including those that may involve KRT110, have been linked to a variety of skin and hair disorders. These conditions can range in severity and present with symptoms such as blistering, hair loss, or nail abnormalities. Research into the precise role of KRT110 and its interactions with other keratins is ongoing to better understand its contribution to cellular structure and its potential involvement in disease.