JumonjiC
JumonjiC is a family of enzymes that play a crucial role in epigenetics, specifically in the demethylation of histone tails. These enzymes are a type of JmjC domain-containing protein, characterized by a conserved JmjC domain that is essential for their catalytic activity. JumonjiC proteins are known to remove methyl groups from lysine residues on histone proteins, which in turn affects gene expression by altering chromatin structure.
The activity of JumonjiC enzymes is vital for a wide range of cellular processes, including cell differentiation,
There are many different JumonjiC proteins in humans and other organisms, each with varying substrate specificities