Ire

Ire is a noun meaning intense anger or wrath. In modern English it is used largely in formal or literary contexts. Historically it appears in phrases such as “to vent one’s ire.”

As an acronym, IRE has referred to various organizations and concepts. The most widely recognized is the Institute of Radio Engineers, a professional society founded in the early 20th century; it merged with the American Institute of Electrical Engineers (AIEE) to form the Institute of Electrical and Electronics Engineers (IEEE) in 1963.

In molecular biology, IRE stands for Iron-Responsive Element, a conserved RNA motif found in transcripts involved in iron metabolism. IREs form stem-loop structures that are bound by Iron Regulatory Proteins, modulating translation or stability depending on iron levels.

Other uses exist in various fields, but no single definition covers all cases; the intended meaning must be inferred from context.