IntegrinProteins
Integrins are a large family of cell surface receptors that play a crucial role in cell adhesion, migration, and signaling. They are heterodimeric proteins, meaning each integrin is composed of two distinct subunits, an alpha (α) subunit and a beta (β) subunit, linked non-covalently. There are at least 18 known α subunits and 8 known β subunits in mammals, which can combine in various ways to form over 24 different integrin heterodimers.
These receptors are transmembrane proteins, with one end exposed to the extracellular environment and the other
Intracellularly, integrins link to the actin cytoskeleton through a complex network of adaptor proteins. This physical