Hisztamint

Hisztamint is not a standard term in scientific nomenclature. It most often appears as a misspelling or a Hungarian variant of histamine (hisztamin). Because "hisztamint" is not widely recognized in English-language sources, this article summarizes what is known about histamine, the biogenic amine that is usually meant.

Histamine is produced primarily by mast cells and basophils, and it also functions as a neurotransmitter in certain brain regions. In the immune system, histamine release contributes to allergy and inflammation by increasing vascular permeability, promoting smooth muscle contraction, and causing symptoms such as itching and redness.

Histamine signals through four receptor subtypes—H1, H2, H3, and H4—each with distinct roles. H1 receptors mediate allergy symptoms and bronchoconstriction, H2 receptors regulate gastric acid secretion, H3 receptors modulate neurotransmitter release, and H4 receptors influence immune cell activity.

Histamine is rapidly degraded by enzymes such as histamine-N-methyltransferase (HNMT) and diamine oxidase (DAO). In medicine, antihistamines that block H1 receptors are used to treat allergies and motion sickness, while H2 blockers reduce gastric acid production. Histamine is synthesized from histidine by the enzyme histidine decarboxylase.

For those seeking related information, topics such as histamine and histamine receptors provide additional context.