Haptoglobiinipitoisuus

Haptoglobiinipitoisuus refers to the concentration of haptoglobin in a biological sample, typically blood serum. Haptoglobin is a protein that binds to free hemoglobin. Hemoglobin is released from red blood cells when they are destroyed, a process called hemolysis. By binding to free hemoglobin, haptoglobin acts as a scavenger, preventing the harmful effects of unbound hemoglobin, such as oxidative damage to tissues and loss of iron through the kidneys.

Measuring haptoglobiinipitoisuus is a diagnostic tool used in veterinary medicine, particularly in the assessment of anemia. Low levels of haptoglobin can indicate increased red blood cell destruction, suggesting hemolytic anemia. Conversely, high levels might be seen in certain inflammatory conditions, as haptoglobin is an acute-phase protein, meaning its concentration increases in response to inflammation. The interpretation of haptoglobiinipitoisuus results must be done in conjunction with other clinical signs and laboratory findings. Factors such as liver function, as haptoglobin is synthesized in the liver, can also influence its levels. Reference ranges for haptoglobiinipitoisuus vary depending on the species and the laboratory performing the test.