HOXB7

HOXB7 is a gene that provides instructions for making a protein that is part of a group of genes called homeobox genes. These genes are important for the normal development of the body. The HOXB7 protein acts as a transcription factor, meaning it binds to specific DNA sequences and helps control the activity of other genes. This is crucial during embryonic development for the formation of various tissues and organs. Specifically, HOXB7 plays a role in the development of the reproductive system, kidneys, and the central nervous system. It is also implicated in cell growth and differentiation. Dysregulation or mutations in the HOXB7 gene have been associated with certain cancers, including ovarian and prostate cancer, where it may contribute to tumor progression and metastasis. Research continues to explore the precise functions of HOXB7 and its potential as a therapeutic target.