GiGoProteiinikytkentäisiä
GiGoProteiinikytkentäisiä, often abbreviated as GPCRs, represent a large and diverse family of cell surface receptors. These receptors play a critical role in signal transduction, mediating the cellular response to a vast array of extracellular stimuli. When a signaling molecule, such as a hormone, neurotransmitter, or odorant, binds to a GPCR, it triggers a conformational change in the receptor. This change, in turn, activates an intracellular signaling pathway, typically involving a G protein.
The activated G protein then dissociates and can interact with various downstream effector molecules, such as
GPCRs are involved in numerous physiological processes and are targets for a significant proportion of currently