GAID1

GAID1, also known as G protein-coupled receptor 120, is a protein that in humans is encoded by the GAID1 gene. This gene is located on chromosome 11q13.3. GAID1 is a member of the G protein-coupled receptor (GPCR) family, which plays a crucial role in signal transduction by coupling to heterotrimeric G proteins.

The GAID1 receptor is primarily expressed in the central nervous system, particularly in the hippocampus and cerebellum. Its exact physiological function is not fully understood, but it is believed to be involved in various neurological processes. Studies have suggested that GAID1 may play a role in synaptic plasticity, memory formation, and the regulation of neurotransmitter release.

Mutations in the GAID1 gene have been associated with several neurological disorders, including schizophrenia, bipolar disorder, and autism spectrum disorder. These mutations can lead to altered receptor function, affecting the balance of neurotransmitters and contributing to the pathogenesis of these conditions.

Research on GAID1 is ongoing, with efforts focused on understanding its precise role in the brain and developing potential therapeutic targets for neurological disorders. The identification of GAID1 as a potential biomarker for these conditions is also an area of active investigation.