Fluconazol

Fluconazole is an antifungal medication used to treat a variety of fungal infections. It is a triazole class of medication that inhibits the synthesis of ergosterol, an essential component of fungal cell membranes, ultimately leading to fungal cell death. Fluconazole is available in oral, intravenous, and topical forms.

The medication is primarily used to treat systemic and superficial fungal infections, including vaginal yeast infections, oropharyngeal and esophageal candidiasis, and dermatophyte infections such as athlete's foot and ringworm. Fluconazole is also used to treat fungal infections in immunocompromised individuals, including those with HIV/AIDS and undergoing chemotherapy.

Fluconazole is administered once or twice daily, depending on the indication and severity of the infection. The typical dosage ranges from 50 to 400 milligrams per day, with the exact dose depending on the specific condition being treated. The medication is usually well tolerated, with common side effects including nausea, headache, and liver enzyme elevations.

Fluconazole has a broad spectrum of antifungal activity, effective against a range of fungal organisms, including Candida, Aspergillus, and Histoplasma. It is also used as prophylaxis to prevent fungal infections in patients with prolonged neutropenia. The long half-life of fluconazole allows for once-daily dosing, making it a convenient treatment option. Studies have shown fluconazole to be effective and safe when used according to the recommended dosing guidelines.