Farmakokinetikáját

Farmakokinetikáját refers to the study of how a drug moves into, through, and out of the body. This process is generally described by four main components: absorption, distribution, metabolism, and excretion, often abbreviated as ADME. Absorption is the process by which a drug enters the bloodstream from its site of administration. Distribution describes how the drug spreads throughout the body's tissues and fluids. Metabolism, also known as biotransformation, involves the chemical alteration of the drug, typically by enzymes in the liver, into metabolites. Excretion is the elimination of the drug and its metabolites from the body, primarily through the kidneys in urine or the liver in bile. Understanding the farmakokinetikáját of a drug is crucial for determining appropriate dosages, dosing intervals, and routes of administration to achieve the desired therapeutic effect while minimizing adverse reactions. Factors such as age, disease states, and drug interactions can significantly influence a drug's farmakokinetikáját.