FHR
Fhr is an initialism used in different fields to denote unrelated concepts. In biomedical contexts, FHR most commonly refers to Factor H-related proteins, a family of plasma glycoproteins that regulate the complement system. The genes encoding these proteins—CFHR1 through CFHR5—are located in a cluster on chromosome 1. FHR proteins are composed of short consensus repeats and are thought to modulate complement activity, often by interacting with Factor H or surface ligands on cells and pathogens. The exact functions of individual FHR family members are not fully resolved, and they may act to fine-tune complement activation on host cells or during infection. Genetic variations in CFHR genes have been associated with susceptibility to diseases such as atypical hemolytic uremic syndrome and certain forms of age-related macular degeneration, though the relationships are complex and under active study. Measurement of circulating FHR proteins can contribute to research and, in some cases, to diagnostic workups, but such testing is not routine in standard clinical practice.
Outside biology, Fhr can serve as an acronym for organizations, projects, or systems, depending on context. Because