F41

F41 is a category in the ICD-10 classification system used to code anxiety disorders that are not phobic in nature. It sits within the mental and behavioral disorders chapter and is designated as “Other anxiety disorders.” The F41 block covers several non-phobic anxiety conditions that may present with excessive worry, fear, or tension and can vary in duration and functional impact.

The main subcodes under F41 include:

- F41.0 Panic disorder: recurrent, unexpected panic attacks and ongoing concern about having more attacks or a change in behavior related to the attacks.

- F41.1 Generalized anxiety disorder: persistent, excessive worry and anxiety about multiple domains (e.g., work, health) for most days over several months, with accompanying physical or cognitive symptoms.

- F41.2 Mixed anxiety and depressive disorder: prominent anxiety symptoms mixed with depressive features that do not meet full criteria for a separate mood disorder.

- F41.8 Other specified anxiety disorders: includes anxiety presentations that do not fit the above categories but are clinically significant.

- F41.9 Anxiety disorder, unspecified: used when insufficient information prevents a more precise coding.

Clinical features commonly associated with F41 disorders include restlessness, fatigue, sleep disturbance, concentration difficulties, and irritability. They often co-occur with mood disorders, substance use, or other medical conditions, and treatment typically involves psychotherapy (notably cognitive-behavioral therapy) and pharmacotherapy such as selective serotonin reuptake inhibitors or serotonin-norepinephrine reuptake inhibitors, tailored to the individual’s symptoms and comorbidities.

In clinical coding, F41 codes are used to document and study these conditions for diagnosis, treatment planning, and insurance purposes. ICD-11 has since reorganized anxiety disorders, offering updated diagnostic structures in newer coding systems.