Endothelsejteket

Endothelsejteket, also known as endothelial cells, form the inner lining of all blood and lymphatic vessels. These cells are crucial for maintaining vascular health and function. They form a semipermeable barrier that regulates the passage of substances between the blood and surrounding tissues. Endothelial cells also play a vital role in hemostasis, the process of blood clotting, by producing factors that either promote or inhibit clot formation.

Beyond their barrier and hemostatic functions, endothelsejteket are active participants in the immune system. They can express adhesion molecules that attract white blood cells to sites of inflammation or infection. Furthermore, these cells are involved in the production of various signaling molecules, including vasodilators and vasoconstrictors, which help regulate blood pressure and blood flow.

Dysfunction of endothelsejteket is implicated in a wide range of diseases. Conditions such as atherosclerosis, hypertension, diabetes, and sepsis are associated with impaired endothelial function. This impairment can lead to increased vascular permeability, inflammation, thrombosis, and reduced ability of blood vessels to dilate. Research into understanding and restoring endothelial function is an active area of medical science, aiming to develop new therapeutic strategies for cardiovascular and other diseases.