Endostéales

Endostéales refers to the layer of cells lining the inner surfaces of bones. This includes the trabecular surfaces within cancellous bone and the medullary cavity of long bones. The endosteum is a thin, cellular membrane composed of a single layer of osteogenic cells, osteoblasts, osteoclasts, and a small amount of connective tissue. Its primary function is bone remodeling, a continuous process of bone resorption by osteoclasts and bone deposition by osteoblasts. This remodeling allows bone to adapt to mechanical stress, repair micro-damage, and maintain mineral homeostasis. The endosteal cells play a crucial role in this dynamic process, differentiating into osteoblasts to form new bone or contributing to the maintenance of the bone surface. The endosteum is also involved in the regulation of bone cell activity through the secretion of various growth factors and signaling molecules. Its integrity and function are essential for maintaining bone strength and health throughout life.