Endocitás

Endocitás is a biological process by which cells absorb molecules from outside the cell by engulfing them with their cell membrane. This process is essential for many cellular functions, including nutrient uptake, immune response, and cellular communication. Endocitosis can be broadly categorized into three main types: phagocytosis, pinocytosis, and receptor-mediated endocytosis.

Phagocytosis, or "cell eating," involves the engulfment of large particles, such as bacteria or cellular debris, by specialized cells like macrophages. The cell membrane extends outwards to form pseudopods that surround and internalize the particle within a large vesicle called a phagosome.

Pinocytosis, or "cell drinking," is a less selective process where the cell membrane invaginates, forming small vesicles that contain extracellular fluid and dissolved solutes. This process allows cells to take in nutrients and water.

Receptor-mediated endocytosis is a highly specific process that relies on the binding of specific molecules (ligands) to receptors on the cell surface. Once bound, these ligand-receptor complexes cluster in specific regions of the membrane, triggering the formation of vesicles that internalize the bound molecules. This mechanism is crucial for the uptake of essential substances like cholesterol and certain hormones.

All forms of endocytosis require energy and are therefore active processes. The internalized vesicles are then processed within the cell, either for degradation, recycling, or signaling. Endocitosis plays a vital role in maintaining cellular homeostasis and interacting with the external environment.