Elp1containing

Elp1containing is a term that refers to the presence or association of the protein Elp1. Elp1, also known as KIAA0564, is a protein involved in various cellular processes. Its primary role is as a subunit of the Elongator complex, a highly conserved multi-protein complex found in eukaryotes. The Elongator complex is known to play critical roles in transcription, including the regulation of gene expression and chromatin remodeling. It also has functions in tRNA modification, which is essential for protein synthesis. Furthermore, Elp1 has been implicated in cellular responses to stress and DNA damage. Research into Elp1containing entities often investigates its localization within the cell, its interactions with other proteins, and its contribution to cellular health and disease. Dysregulation of Elp1 or the Elp1containing Elongator complex has been linked to several developmental disorders and certain types of cancer, highlighting its importance in maintaining cellular homeostasis. Therefore, understanding Elp1containing contexts is crucial for comprehending fundamental cellular mechanisms and for developing potential therapeutic strategies for associated pathologies.