DrugdeliveryTrägermaterialien
DrugdeliveryTrägermaterialien, commonly referred to as drug delivery carrier materials, are substances used to transport therapeutic agents to specific sites in the body, enabling controlled release, improved stability, and enhanced bioavailability. They are engineered to carry drugs, genes, or vaccines and release them under predefined conditions.
Carrier materials encompass organic and inorganic systems, including polymeric carriers (poly(lactic-co-glycolic acid) PLGA, polycaprolactone, PEGylated polymers),
Key design considerations include biocompatibility and biodegradability, particle size and surface charge, payload capacity, and release
Applications span oncology, vaccines, gene therapy, nervous system delivery, and regenerative medicine. Approved products, particularly liposomal
Challenges include potential toxicity and immunogenicity, manufacturing scalability, reproducibility, and regulatory requirements for characterization and stability.