DefaultMertk
DefaultMertk is a specialized protein encoded by the MERTK gene in humans. It belongs to the receptor tyrosine kinase (RTK) family, which plays a critical role in various cellular processes, including cell proliferation, survival, migration, and immune regulation. Mertk is primarily expressed in immune cells such as macrophages, dendritic cells, and certain epithelial cells.
The MERTK protein is integral to the clearance of apoptotic cells, a process known as efferocytosis. By
Mutations or dysregulation of the MERTK gene have been associated with various pathological conditions. For instance,
Research on Mertk continues to explore its potential as a therapeutic target, especially in cancers and autoimmune
Overall, DefaultMertk is a crucial component in immune regulation and tissue maintenance, with significant implications for