ClinicalTrialsgov

ClinicalTrials.gov is a registry and results database of publicly and privately funded clinical studies involving human participants. It is hosted by the National Library of Medicine (NLM) at the United States National Institutes of Health (NIH). The site provides a free, publicly accessible platform to register clinical trials and post study results, with the aim of increasing transparency and accessibility of trial information for researchers, clinicians, patients, and policymakers.

The database covers a wide range of study types, including interventional trials, observational studies, and expanded access programs. Each registered study receives a unique NCT identifier and includes fields such as condition, intervention, sponsor, locations, study design, phase, enrollment, eligibility criteria, outcome measures, and enrollment status. The search interface supports queries by condition, intervention, sponsor, location, and other criteria.

ClinicalTrials.gov began operation in 2000 and is administered by the NLM at NIH. U.S. law requires the registration and results reporting of certain applicable trials, notably under the FDA Amendments Act of 2007, with implementing rules in 2016. The site provides both protocol registration data and results reporting, including summaries of primary outcomes and, in many cases, adverse events.

The database offers API access and data exports for programmatic use, alongside human-readable trial records. Data quality can vary because records depend on sponsor and investigator submissions and ongoing updates. The registry is widely used for literature reviews, clinical decision-making, and policy analysis, though it does not guarantee complete coverage of all trials or fully up-to-date results for every entry.