Cefadroxil

Cefadroxil is a first-generation cephalosporin antibiotic used to treat various bacterial infections. It is a semi-synthetic derivative of Cephalosporin C, which is originally found in the fungus Cephalosporium acremonium. The medication is effective against a wide range of Gram-positive and Gram-negative bacteria, including those that are resistant to other antibiotics.

Cefadroxil is administered orally, typically in the form of capsules or suspension. It is usually taken once or twice a day, depending on the severity of the infection. The medication is well absorbed from the gastrointestinal tract, and the peak plasma concentration is reached within 2-4 hours after administration. Cefadroxil is primarily excreted through the kidneys, and its half-life is approximately 12-19 hours.

Cefadroxil is used to treat various infections, including skin and soft tissue infections, urinary tract infections, and respiratory tract infections. It is also effective against acne, gonorrhea, and Lyme disease. However, the medication is not indicated for use against life-threatening infections, such as meningitis or septicemia, or for patients with impaired kidney function.

Common side effects of cefadroxil include gastrointestinal disturbances, such as nausea and diarrhea, as well as skin reactions like rashes and pruritus. More severe side effects, such as allergic reactions, can occur in rare cases. Patients with a history of penicillin allergy should exercise caution when taking cefadroxil, as cross-reactivity can occur. The medication is generally well-tolerated, but it is essential to follow the recommended dosage and duration of treatment to minimize the risk of adverse effects.