Calithera
Calithera is a biopharmaceutical company focused on developing novel small molecule drugs targeting cancer metabolism. The company's primary approach is to identify and inhibit specific enzymes and pathways that cancer cells rely on for their rapid growth and proliferation, while aiming to spare healthy cells. Their pipeline includes drug candidates in various stages of clinical development for different types of cancer.
The company's lead programs are centered around inhibitors of glutaminase, an enzyme involved in the metabolism
Calithera also explores other metabolic targets in cancer, seeking to exploit vulnerabilities unique to cancerous cells.