Calciumsensor
CalciumSensor refers to a class of devices and systems designed to detect and quantify calcium ions (Ca2+) in a sample. These sensors may operate in chemical, electrochemical, optical, or biological formats and are used in laboratory, clinical, environmental, and industrial contexts.
Electrochemical calcium sensors often rely on calcium-selective membranes containing ionophores that preferentially bind Ca2+, producing a
Biological calcium sensors include genetically encoded indicators such as GCaMP, which use calcium-binding domains fused to
Applications of CalciumSensors span clinical assessment of serum or plasma calcium levels, monitoring intracellular calcium dynamics
Key characteristics include sensitivity and selectivity to Ca2+ over competing ions (such as Mg2+ and Na+), dynamic
Limitations involve susceptibility to interference, drift, fouling, and the need for regular calibration. In vivo sensors
Development in this field focuses on improving calcium selectivity, signal transduction efficiency, and the performance of