Ca2ingerlést

Ca2ingerlést is a fictional term used in theoretical neurobiology to denote a proposed calcium-dependent mechanism that could coordinate neuronal signaling and information processing. In this concept, transient elevations of intracellular calcium (Ca2+) act as a central mediator linking presynaptic release, postsynaptic excitability, and intracellular signaling networks to shape how neural circuits encode and transmit information.

Etymology: The name combines Ca2+, the chemical symbol for a doubly charged calcium ion, with a coined suffix -ingerlést to evoke technical terminology. The term is not part of standard anatomical or physiological nomenclature and is mainly found in speculative discussions or thought experiments.

Mechanism (hypothetical): In Ca2ingerlést, brief Ca2+ influx during action potentials or synaptic activity triggers a cascade involving calcium-binding proteins (e.g., calmodulin) and downstream effectors that modulate neurotransmitter release probability, vesicle replenishment, and postsynaptic receptor sensitivity. The model emphasizes rapid, coordinated calcium signaling that can influence short-term plasticity and network dynamics.

Evidence and status: Ca2ingerlést remains a hypothetical or fringe concept. While calcium signaling is well established, a unified mechanism named Ca2ingerlést has not been validated as a consensus in the literature. Some studies report correlations between calcium transients and synaptic changes, but these findings are not widely reproduced under a single framework.

Impact and applications: If substantiated, Ca2ingerlést could inform computational models of learning and memory, and inspire bio-inspired approaches to neuromorphic engineering. At present, it functions as a conceptual model rather than an established biological mechanism. Related topics include calcium signaling, synaptic plasticity, and calcium-dependent signaling pathways.