CSFvolymen

CSFvolymen, or cerebrospinal fluid volume, refers to the total amount of cerebrospinal fluid contained within the brain’s ventricular system and the surrounding subarachnoid spaces from the brain down the spinal canal. It is a fundamental parameter in understanding cerebral fluid dynamics and overall intracranial homeostasis.

In healthy adults, the total CSF volume is typically about 120 to 150 milliliters. The ventricular system holds a portion of this volume, while the majority resides in the subarachnoid space surrounding the brain and spinal cord. CSF is produced mainly by the choroid plexus at a rate of about 0.3 to 0.4 milliliters per minute (roughly 500 milliliters per day). It circulates from the ventricles through the foramina into the subarachnoid space and is reabsorbed primarily via arachnoid granulations into the venous circulation.

CSF volume is not fixed; it can vary with age, body size, and physiological or pathological states. Disruptions in production, flow, or absorption can alter CSF volume and lead to changes in intracranial pressure, as seen in conditions such as hydrocephalus or intracranial hypotension. Precise measurement of total CSF volume is not routine in clinical practice but can be estimated using imaging techniques in research or specialized diagnostic settings.

Overall, CSFvolymen reflects the balance between production and absorption of cerebrospinal fluid and plays a key role in protecting, nourishing, and maintaining the homeostatic environment of the central nervous system.